Natalie - Revision history

imported>Psych204B: /* Run3-Motion Spikes Regressed Out */

2012-03-17T00:58:51Z

Run3-Motion Spikes Regressed Out

← Older revision		Revision as of 00:58, 17 March 2012
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	Adding these regressors did not completely remove the effects of motion from the statistical maps and FFA is not present in these maps.		Adding these regressors did not completely remove the effects of motion from the statistical maps and FFA is not present in these maps.

	""The Variance Contributed by Motion Spikes""		''''The Variance Contributed by Motion Spikes''''
	[[File:EffectsofSpikes.jpg]]		[[File:EffectsofSpikes.jpg]]

imported>Psych204B at 00:53, 17 March 2012

2012-03-17T00:53:47Z

← Older revision		Revision as of 00:53, 17 March 2012
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	[[File:Ctl1-Run1.jpg]]		[[File:Ctl1-Run1.jpg]]

			The motion parameters helped by removing noise, however, this may be task-related activation, therefore further analyses are necessary to determine whether or not this is the best step.

	===Run2===		===Run2===

			This subject has significant spikes towards the end of the run, so further analyses are necessary to remove the effects of motion.

	[[File:Ctl1-Run2.jpg]]		[[File:Ctl1-Run2.jpg]]

	===Run3===		===Run3===

			This subject has significant spikes in the middle of the run, so further analyses are necessary to remove the effects of motion.

	[[File:Ctl1-Run3.jpg]]		[[File:Ctl1-Run3.jpg]]

	===Run4===		===Run4===

			The motion for this subject was not terrible and therefore, I decided that using the motion parameters as regressors would suffice here.

	[[File:Ctl1-Run4.jpg]]		[[File:Ctl1-Run4.jpg]]

			After adding motion regressors to these maps, there is still very little activation. This may be due to the subject's inattention, as this is the end of a 35 minute task. However, there could be multiple reasons that this subject does not show significant activation.

	== Simple Model GLM Results for a Subject with Significant Motion using "Motion Corrected" Data ==		== Simple Model GLM Results for a Subject with Significant Motion using "Motion Corrected" Data ==
	===Run2-Motion Volumes Removed===		===Run2-Motion Volumes Removed===

			With this run, I attempted to correct for the effects of motion by removing the last 15 TRs from the raw dataset, and proceeded with preprocessing and GLM analyses.

	[[File:Ctl1-AfterVolsRem.jpg]]		[[File:Ctl1-AfterVolsRem.jpg]]

			Removing these movement TRs helped the analyses, but did not completely remove the effects of motion from the statistical maps and FFA is not present in these maps.

	===Run3-Motion Spikes Regressed Out===		===Run3-Motion Spikes Regressed Out===


			With this run, I attempted to correct for the effects of motion by adding nuisance regressors to remove the variance associated with the motion spikes.

	[[File:Run3-SpikesRegressed.jpg]]		[[File:Run3-SpikesRegressed.jpg]]

			Adding these regressors did not completely remove the effects of motion from the statistical maps and FFA is not present in these maps.

	""The Variance Contributed by Motion Spikes""		""The Variance Contributed by Motion Spikes""
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	==Fixed Effects Model with all 4 Runs w/ Motion Correction==		==Fixed Effects Model with all 4 Runs w/ Motion Correction==

	[[File:Ctl1-All4RunsCombined.jpg]]		[[File:Ctl1-All4RunsCombined.jpg]]

	= Conclusions =		= Conclusions =

	- Using motion parameters as regressors can help clean up your data		Using motion parameters as regressors can help clean up your data
	~~Using any kind of motion correction cannot salvage a subject with excessive motion (>3 mm for this project)~~

	~~- Here is where you say what your results mean.~~		However, using any kind of motion correction cannot salvage a subject with excessive motion (>3 mm for this project)

	= References =		= References =

imported>Psych204B at 05:17, 16 March 2012

2012-03-16T05:17:19Z

← Older revision		Revision as of 05:17, 16 March 2012
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	To date, no studies have examined the neural components of inhibitory processing during an emotional GNG task in adolescents who are currently experiencing a major depressive episode. In the present study we will use an emotion-modified GNG task to examine the neural correlates of inhibitory behavior in adolescents diagnosed with MDD. Either an emotional face or an emotionally neutral tree will be presented for 1 s before the target, allowing for an examination of the effects of emotional processing on inhibitory control. Presenting the emotional face prior to the response target will permit the separation of the effects of emotional processing from those of inhibitory control.		To date, no studies have examined the neural components of inhibitory processing during an emotional GNG task in adolescents who are currently experiencing a major depressive episode. In the present study we will use an emotion-modified GNG task to examine the neural correlates of inhibitory behavior in adolescents diagnosed with MDD. Either an emotional face or an emotionally neutral tree will be presented for 1 s before the target, allowing for an examination of the effects of emotional processing on inhibitory control. Presenting the emotional face prior to the response target will permit the separation of the effects of emotional processing from those of inhibitory control.

			For the purposes of this project, I am interested in the effects that motion and motion correction have on the results of my experiment. Therefore, I will examine two subjects, one with minimal motion and one with an extreme amount of motion, and attempt to correct this motion with multiple methods. I will use the contrast Emotional Go > Tree Go in order to use the presence of the FFA as a signal of effective motion correction in the data.

	= Methods =		= Methods =

imported>Psych204B: /* Fixed Effects Model with all 4 Runs w/ Motion Correction */

2012-03-16T05:14:24Z

Fixed Effects Model with all 4 Runs w/ Motion Correction

← Older revision		Revision as of 05:14, 16 March 2012
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	==Fixed Effects Model with all 4 Runs w/ Motion Correction==		==Fixed Effects Model with all 4 Runs w/ Motion Correction==
	[[Ctl1-All4RunsCombined.jpg]]		[[File:Ctl1-All4RunsCombined.jpg]]

	= Conclusions =		= Conclusions =

imported>Psych204B: /* References */

2012-03-16T05:14:05Z

References

← Older revision		Revision as of 05:14, 16 March 2012
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	= References =		= References =
			Kessler, R. & Wang, P. The Epidemiology of Depression. The Handbook of Depression. New York: Guilford; 2009.

			Kessler, R.C., Avenevoli, S. & Merikangas, K.R. (2001). Mood disorders in children and adolescents: an epidemiologic perspective. Biological Psychiatry, 49, 1002-1014.

			Lewinsohn PM, Rohde P, Seeley JR. (1998). Treatment of adolescent depression: frequency of services and impact on functioning in young adulthood. Depression and Anxiety. 7(1), 47-52.

			Rao, U., Hammen, C. & Daley, S.E. (1999). Continuity of depression during the transition to adulthood: A 5-year longitudinal study of young women. Journal of the American Academy of Child and Adolescent Psychiatry, 38, 908-015.

			Weissman, M.M., Wolk, S., Goldstein, R.B., Moreau, D., Adams, P., Greenwald, S., Klier, C.M., Ryan, N.D., Dahl, R.E., Wickramaratne, P. (1999). Depressed adolescents grown up. Journal of the American Medical Association, 281, 1707-1713.

			Lewinsohn, P.M., Rohde, P., Seeley, J.R., Klein, D.N. & Gotlb, I.H. (2003). Psychosocial functioning of young adults who have experienced and recovered from major depressive disorder during adolescence. Journal of Abnormal Psychology, 112(3), 353-363.

			Arnett, J.J. (1999). Adolescent storm and stress, reconsidered. American Psychologist, 54(5), 317-326.

			Larson, R. & Richards, M.H. (1994). Divergent realities: The emotional lives of mothers, fathers, and adolescents. New York: Basic Books.

			Galvan, A. Hare, T.A. Parra, C.E., Penn, J., Voss, H., Glover, G., Casey, B.J. (2006). Earlier development of the accumbens relative to orbitofrontal cortex might underlie risk-taking behavior in adolescents. Journal of Neuroscience, 26, 6885-6892.

			Guyer, A.E., Monk, C.S., McClure-Tone, E.B., Nelson, E.E., Roberson-Nay, R., Adler, A.D., Fromm, S.J., Liebenluft, E., Pine, D.S. & Ernst, M. (2008). A developmental examination of amygdala response to facial expressions. Journal of Cognitive Neuroscience, 20(9), 1565-1582.

			Monk, C.S., McClure, E.B., Nelson, E.E., Zarahn, E., Bilder, R.M., Leibenluft, E., Charney, D.S., Ernst, M. & Pine, D.S. (2003). Adolescent immaturity in attention-related brain engagement to emotional facial expressions. NeuroImage, 20, 420-428.

			Joormann, J., Talbot, L. & Gotlib, I.H. (2007) Biased processing of emotional information in girls at risk for depression. Journal of Abnormal Psychology, 116(1), 135-143.

			Casey, B.J., Trainor, R.J., Orendi, J.L., Schubert, A.B., Nystrom, L.E., Giedd, J.N., Castellanos, F.X., Haxby, J.V., Noll, D.C., Cohen, J.D., Forman, S.D., Dahl, R.E. & Rapoport, J.L. (1997). A developmental functional mri study of prefrontal activation during performance on a go-no-go task. Journal of Cognitive Neuroscience, 9(6), 835,847.

			Durston, S., Thomas, K.M., Yang, Y., Ulug, A.M., Zimmerman, R.D. & Casey, B.J. (2002). A neural basis for the development of inhibitory control. Developmental Science, 5(4), F9-F16.

			Hare, T.A., Tottenhan, N., Galvan, A., Voss, H.U., Glover, G.H. & Casey, B.J. (2008). Biological substrates of emotional reactivity and regulation in adolescence during an emotional go-nogo task. Biological Psychiatry, 63, 927-934.

imported>Psych204B: /* Background */

2012-03-16T05:08:55Z

Background

← Older revision		Revision as of 05:08, 16 March 2012
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	To date, no studies have examined the neural components of inhibitory processing during an emotional GNG task in adolescents who are currently experiencing a major depressive episode. In the present study we will use an emotion-modified GNG task to examine the neural correlates of inhibitory behavior in adolescents diagnosed with MDD. Either an emotional face or an emotionally neutral tree will be presented for 1 s before the target, allowing for an examination of the effects of emotional processing on inhibitory control. Presenting the emotional face prior to the response target will permit the separation of the effects of emotional processing from those of inhibitory control.		To date, no studies have examined the neural components of inhibitory processing during an emotional GNG task in adolescents who are currently experiencing a major depressive episode. In the present study we will use an emotion-modified GNG task to examine the neural correlates of inhibitory behavior in adolescents diagnosed with MDD. Either an emotional face or an emotionally neutral tree will be presented for 1 s before the target, allowing for an examination of the effects of emotional processing on inhibitory control. Presenting the emotional face prior to the response target will permit the separation of the effects of emotional processing from those of inhibitory control.


	~~Once you upload the images, they look like this. Note that you can control many features of the images, like whether to show a thumbnail, and the display resolution.~~
	~~[[File:Example3.jpg \|thumb\|300px\|center\| Figure 3]]~~
	~~<br>~~


	= Methods =		= Methods =

imported>Psych204B at 05:05, 16 March 2012

2012-03-16T05:05:38Z

← Older revision		Revision as of 05:05, 16 March 2012
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	[[File:Ctl1-Run4.jpg]]		[[File:Ctl1-Run4.jpg]]

	== ~~Fixed Effects~~ GLM Results for a Subject with Significant Motion using "Motion Corrected" Data ==		== Simple Model GLM Results for a Subject with Significant Motion using "Motion Corrected" Data ==
	~~Some text~~. ~~Some analysis~~. ~~Some figures~~.		===Run2-Motion Volumes Removed===
			[[File:Ctl1-AfterVolsRem.jpg]]

			===Run3-Motion Spikes Regressed Out===
			[[File:Run3-SpikesRegressed.jpg]]


			""The Variance Contributed by Motion Spikes""
			[[File:EffectsofSpikes.jpg]]

			==Fixed Effects Model with all 4 Runs w/ Motion Correction==
			[[Ctl1-All4RunsCombined.jpg]]

	= Conclusions =		= Conclusions =

	~~Here is where you say what~~ your ~~results mean.~~		- Using motion parameters as regressors can help clean up your data
			Using any kind of motion correction cannot salvage a subject with excessive motion (>3 mm for this project)

	~~= References~~ - ~~Resources and related work =~~		- Here is where you say what your results mean.

	References		= References =

imported>Psych204B: /* Fixed Effects GLM Results for a Subject with Significant Motion */

2012-03-15T22:29:23Z

Fixed Effects GLM Results for a Subject with Significant Motion

← Older revision		Revision as of 22:29, 15 March 2012
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	[[File:Ctl1-Run4.jpg]]		[[File:Ctl1-Run4.jpg]]

	== Fixed Effects GLM Results for a Subject with Significant Motion ==		== Fixed Effects GLM Results for a Subject with Significant Motion using "Motion Corrected" Data ==
	Some text. Some analysis. Some figures.		Some text. Some analysis. Some figures.

imported>Psych204B at 22:28, 15 March 2012

2012-03-15T22:28:47Z

@@ Line 96: / Line 96: @@
 [[File:Ctl1-Run4.jpg]]
-== Retinotopic models in individual subjects transformed into MNI space ==
+== Fixed Effects GLM Results for a Subject with Significant Motion ==
 Some text. Some analysis. Some figures.
@@ Line 130: / Line 106: @@
 References

imported>Psych204B at 22:27, 15 March 2012

2012-03-15T22:27:40Z

← Older revision		Revision as of 22:27, 15 March 2012
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	[[File:Ctl1-Run1.jpg]]		[[File:Ctl1-Run1.jpg]]

	==Run2==		===Run2===

	[[File:Ctl1-Run2.jpg]]		[[File:Ctl1-Run2.jpg]]

	==Run3==		===Run3===

	[[File:Ctl1-Run3.jpg]]		[[File:Ctl1-Run3.jpg]]

	==Run4==		===Run4===

	[[File:Ctl1-Run4.jpg]]		[[File:Ctl1-Run4.jpg]]