Introduction
Clinical Motivation
Problem Statement
Background
Previous Work
Optical Tissue Properties in the Literature
| Tissue Layer |
μa [cm⁻¹] 420 nm |
μs [cm⁻¹] 420 nm |
μa [cm⁻¹] 450 nm |
μs [cm⁻¹] 450 nm
|
| Superficial epithelium |
3.0 |
170 (keratinized) / 55 (non keratinized) |
2.1 |
140 (keratinized) / 40 (non keratinized)
|
| Intermediate epithelium |
3.0 |
55 |
2.1 |
40
|
| Basal epithelium |
3.0 |
55 |
2.1 |
40
|
| Superficial stroma |
6.22 |
267 |
3.11 |
248.5
|
| Deep stroma |
6.22 |
267 |
3.11 |
248.5
|
| Blood |
262 |
37.8 |
30 |
31.1
|
Methods
Monte Carlo Simulation Principle
|
|
| (a) Definition of the geometric domain
|
(b) Random point generation, classification, and counting
|
| Figure 1: Basic Monte Carlo simulation to compute π
|
Monte Carlo Simulation for Light Propagation
|
|
|
|
| (a) Launching a photon packet
|
(b) Straight-line propagation over a free path
|
(c) Interaction event
|
(d) Updating the Photon Weight
|
| Figure 2: Monte Carlo simulation for light
|
Monte Carlo Matlab
Five Layer Model and Geometry
Results
Comparison Between Keratinized and Non-Keratinized Tissues
Fluence Results
Fluence Distribution
Figure 3: Fluence comparison between keratinized and non-keratinized tissue
Absorbance Results
Reflectance Results
Influence of Blood Depth on the Optical Response
Fluence Results
Absorbance Results
Reflectance Results
Discussion and Conclusions
Appendix
Our code can be found at (Github link).
