Mai

Introduction to retinotopy

Early visual areas, located in the posterior occipital lobe, are retinotopically organized: A particular location in the early visual cortex responds to stimulation at a particular location in the visual field, while neighboring locations on the cortical surface respond to neighboring locations in the visual field. This pattern of response maps a representation of the visual field onto the cortical surface.

Retinotopic areas on example subject

These early visual areas are mapped with two parameters: eccentricity and polar angle. Eccentricity indicates distance from fovea. The most posterior regions of the early visual areas has a pronounced foveal preference, while more anterior regions prefer more eccentric stimuli. In visualizations of retinotopy, eccentricity mapping appears as concentric "rings" of different colors, each denoting a different eccentricity. Polar angle indicates the angle from the horizontal meridian, so polar angle mapping shows the reversals in angular representations on the cortex, which are used in defining retinotopic maps.

While the primary visual cortex (V1) was the first visual field map discovered, over the last 15 years, a variety of retinotopic maps have been identified on the ventral and dorsal surface of visual cortex. While definitions of these visual areas will not be discussed, more information about these retinotopic maps can be found here. Information about defining these regions can be found here and here.

Traveling wave model

While retinotopic maps were first identified in the 1940s ago using electrophysiology, it is only in the last 20 years that these maps have been identified using fMRI. The turning point was in 1994 when Engel, Glover, and Wandell developed a new method for mapping visual field maps using a "traveling wave" of activation. First used to map eccentricity in V1, this method was a vast improvement on previous methods. In a nutshell, this method activates different regions of the visual cortex at different times, creating a "traveling wave" of activation from one region to another. The delay in activation allows us to infer the eccentricity or polar angle preference of a region. So how does this actually work?

The Stimuli

Early visual cortex has both eccentricity and polar angle mapping, so two types of stimuli are needed. Eccentricity is mapped using a series of expanding, concentric checkerboard rings while polar angle is mapped by a rotating checkerboard wedge. These checkerboard patterns have been demonstrated to generate a strong neural response in early visual areas.

Stimuli used in mapping polar angle (top) and eccentricity (bottom)